
Glycine — The Gentle Powerhouse for Sleep, Collagen & Detox
A foundational amino acid for deep sleep, connective tissue resilience & healthy detoxification.
What Is Our Glycine Supplement and Why It’s Powerful:
Glycine supports healthy sleep quality, collagen formation for joints & skin, and cellular detox through glutathione & bile-acid pathways. Sleep deeper, move easier, recover cleaner— all by restoring an amino acid many modern diets undersupply.
Glycine is the simplest amino acid, yet it plays outsized roles in human biology. It is a structural building block of collagen, a co‑factor in glutathione synthesis, a conjugate for bile acids, and a calming neurotransmitter-like signal that supports comfortable sleep and balanced stress responses. Glycine also participates in methylation balance via the glycine‑cleavage system and contributes to creatine and heme synthesis.
Intake often falls short—especially in people who do not regularly consume collagen‑rich foods. Supplementing glycine helps support restorative sleep, skin elasticity & joint comfort, detox capacity, and metabolic steadiness. It’s a smart daily choice for those focused on longevity, performance, and graceful aging.
⚠️ For anyone concerned about restorative sleep, connective tissue integrity, or healthy detoxification, Glycine may be one of the most underrated supplements to know about. It supports normal sleep architecture, collagen matrix renewal, glutathione status, and bile flow—making it a strategic investment in vitality & recovery.
Purity plus Benefits
Pure Glycine (potency & count to be finalized)
Our glycine is USP-grade and third‑party tested for identity, purity, and potency. Glycine is abundant in connective tissues and the central nervous system, where it supports collagen structure, neurotransmission balance, and cellular detox chemistry.
- cGMP manufacturing in the USA
- COA on request for every lot
- Vegan capsules, no magnesium stearate, no artificial colors
- Transparent label: no blends, just glycine
Who Glycine Helps Most
- Sleep‑focused adults seeking deeper, more refreshing sleep quality
- Aging adults prioritizing joint comfort, skin elasticity, and recovery
- High‑stress lifestyles needing calm focus without stimulants
- Low‑collagen diets (vegans/vegetarians or low connective‑tissue intake)
- Metabolic & detox support for those optimizing glutathione and bile flow
Why You Should Take Double Wood Glycine
Glycine quietly powers multiple fundamentals of health: it is a primary amino acid in collagen (skin, joints, bones), a required substrate for glutathione (your body’s master antioxidant), a conjugate for bile acids (detox & fat digestion), and a calming co‑agonist at select neuroreceptors—supporting relaxation and healthy sleep.
Many modern diets provide ample methionine from muscle meats but relatively little glycine from collagen‑rich cuts. Strategically supplementing glycine helps restore this natural balance and can support smoother joints, healthier skin, steadier nerves, and cleaner recovery from daily stress.
- Supports deeper, more refreshing sleep quality
- Promotes collagen matrix renewal for joints, skin & bones
- Supports glutathione production & healthy detox pathways
- Helps maintain healthy metabolic & methylation balance
- Calm‑focus neuromodulator effects without sedation for most users
Double Wood Glycine is made in the USA, third‑party tested, and formulated for high purity — no gimmicks, no blends, just glycine.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Why Glycine Outshines Many Other Amino Acids
Unlike most amino acids mainly used to build proteins, glycine is both a structural cornerstone of collagen and a versatile metabolic player. It supports membrane stability, neurotransmission balance, and critical detox pathways.
Glycine makes up roughly one‑third of collagen’s amino acid content, helping maintain resilient tendons, ligaments, cartilage, and skin. It also contributes to creatine, heme, and nucleic acid synthesis, and helps buffer the methylation cycle via the glycine‑cleavage system.
People commonly report calmer evenings, smoother joint comfort, and a “cleaner” recovery feel when adding daily glycine—especially when dietary collagen is low.
Why Glycine Is a Cornerstone for Lifelong Vitality
Glycine influences how you feel and function every day: it supports normal sleep architecture, helps your body manufacture glutathione, and keeps collagen tissues resilient. Adequate glycine intake can complement an active lifestyle and healthy aging plan.
Well‑supported benefits include:
- Helps maintain healthy sleep quality & nighttime relaxation
- Supports joint comfort, skin elasticity, and connective‑tissue integrity
- Supports glutathione status & phase‑II detox conjugation
- Helps maintain healthy metabolic & methylation balance
- Pairs well with collagen peptides for structural support
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The Many Noticeable Ways Glycine Helps

Supports Deeper, More Refreshing Sleep
- Promotes normal sleep architecture and nighttime relaxation, helping the body cycle smoothly through all restorative stages of sleep.
- May help reduce occasional sleep latency when used before bed, allowing you to drift off more easily and naturally.
- Encourages a calmer mind and steadier focus at night, making it easier to leave behind daily stressors and settle into rest.
- Supports a healthy balance of neurotransmitters involved in relaxation, reducing restless thoughts and nighttime tension.
- Provides calm-focus effects without next-day grogginess for most users, promoting morning clarity and refreshed energy.
- May enhance sleep quality in individuals who occasionally wake during the night, supporting longer periods of uninterrupted rest.
Many adults find that taking glycine in the evening supports the body’s natural ability to settle and experience restorative sleep. By easing the transition into deeper sleep phases and promoting a sense of calm, it helps create a more reliable pattern of nighttime rest. This consistent restoration not only supports energy and focus during the day but also contributes to long-term resilience, recovery, and overall well-being.
Many adults find that taking glycine in the evening supports the body’s natural ability to settle and experience restorative sleep. By easing the transition into deeper sleep phases and promoting a sense of calm, it helps create a more reliable pattern of nighttime rest. This consistent restoration not only supports energy and focus during the day but also contributes to long-term resilience, recovery, and overall well-being.

Promotes Collagen Renewal for Joints, Skin & Bones
Glycine is a major building block of collagen, the structural protein that gives strength and flexibility to connective tissues throughout the body. Adequate glycine intake supports the body’s natural ability to renew and maintain these tissues, contributing to lasting joint comfort, youthful skin, and resilient bones.
- Helps maintain comfortable joints and flexible tendons & ligaments, promoting smooth movement and physical resilience.
- Supports healthy skin elasticity, hydration, and structural integrity, which may contribute to a more youthful appearance.
- Plays a role in bone strength by reinforcing the collagen framework that minerals attach to, helping bones remain durable and less brittle with age.
- Pairs well with collagen peptides and vitamin C, which together maximize the body’s own collagen production and repair processes.
- May aid in recovery after physical stress, exercise, or injury by supporting connective tissue rebuilding and repair.
- Contributes to overall mobility and skin health, reinforcing the body’s foundation from the inside out.

Supports Glutathione & Healthy Detox Pathways
Glycine is an essential co-factor for the body’s production of glutathione, the master antioxidant that safeguards cells from free radicals and supports optimal immune defense. It also combines with bile acids to form bile salts, which are crucial for fat digestion and the clearance of fat-soluble toxins. Together, these processes represent two foundational pillars of the body’s detoxification physiology.
- Supports glutathione production to defend against oxidative stress, preserving mitochondrial function and cellular vitality.
- Assists normal bile flow and promotes effective removal of fat-soluble waste, environmental toxins, and metabolic by-products.
- Complements phase-II conjugation processes in the liver, working synergistically with a diet rich in antioxidants and cruciferous vegetables.
- Plays a role in detoxifying xenobiotics (foreign compounds such as pollutants and chemicals), reducing overall toxic burden.
- Helps maintain a healthy balance of inflammatory mediators by supporting antioxidant capacity and normal redox homeostasis.
- Pairs well with nutrients such as N-acetylcysteine (NAC), vitamin C, and selenium to further reinforce glutathione synthesis and liver resilience.

Helps Maintain Healthy Metabolic & Methylation Balance
- Supports comfortable post-meal steadiness as part of a healthy diet, helping regulate normal blood sugar fluctuations and energy levels.
- Buffers methionine-heavy patterns by restoring glycine balance, which helps maintain optimal methylation capacity and reduces excess metabolic strain.
- Participates in creatine, heme, and nucleic-acid synthesis, supporting muscle energy, red blood cell function, and healthy DNA repair processes.
- Plays a key role in the body’s one-carbon metabolism cycle, assisting in the proper use of nutrients such as folate, B12, and choline for efficient methylation.
- Contributes to balanced homocysteine metabolism, which is important for maintaining cardiovascular health and reducing vascular stress.
- Helps sustain metabolic flexibility, allowing the body to adapt between glucose and fat utilization for steady energy and endurance.
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Glycine


How to Use Glycine
General adult routine — Start with 1,000 mg once or twice daily. Many adults use an evening serving of 2,000–3,000 mg about 60–90 minutes before bed to support sleep quality. Glycine can be taken with or without food.
- Adjustable daily amount | Typical practitioner use is 1,000–5,000 mg/day in divided doses. Increase gradually as needed, ideally with professional guidance.
- Split dosing | Consider a daytime dose for calm focus and an evening dose for sleep support.
- Smart pairings | Glycine stacks well with collagen peptides (structural support), N‑acetyl‑cysteine (glutathione support), magnesium (glycinate or threonate), and vitamin C.
- Consistency | Many notice effects within 3–10 days; connective‑tissue benefits build over 4–8 weeks.
- Notes | Generally well‑tolerated. If you have kidney or liver conditions or use prescription medications, consult your clinician before use.
Videos about Glycine
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